To improve your experience on Lilly TrialGuide, please use the latest version of Chrome, Firefox, Safari, or Internet Explorer, with JavaScript enabled.
This website is not optimized for your browser, as configured.
Collaboration

Clinical Trial History: Human Protections Through the Years and Across the Globe

HistoryOfClinicalTrials1

Clinical research, by its very nature, is continually evolving as we learn through the scientific process and sometimes through human behavior. The Hippocratic Oath, established in 500 BC, bound a physician to uphold professional ethical standards. But this solemnly sworn oath was not a requirement, and it was followed by a long period of stasis. Advances in protections for people in research weren’t put in place until thousands of years later, and often these were developed in response to particular abuses or scandals.

For example, the Nuremburg Code of international ethics was established in 1947 in response to the atrocities of World War II, some of which were committed in the name of science. The 1960s and 1970s gave rise to additional human protections around the globe and made the practice of bioethics more standard.

It may be surprising to realize the protections we expect and perhaps take for granted today are only a few decades old. Take a look at a few key events in the graphic below.

History-Clinical-Trials-Infographic

References:

  1. https://history.nih.gov/about/timelineslawshuman
  2. https://www.fda.gov/media/110437/download
  3. https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report/index
  4. https://wellcomeimages.org/indexplus/image/L0034090
Tags: History, Bioethics, Infographic,

Recent Articles

AHerosJourneyThroughClinicalTrials2-14-2020

A Hero’s Journey Through Clinical Trials

Leigh Anne Naas Headshot
Leigh Anne Naas
February 14th, 20203 minute read

In collaboration with artist John Magnan, we launched a crowd-sourced art project dedicated to clinical trial participants.

InternationalDayofWomenandGirlsinScience FeatureImage 10Feb2020

A STEM Career in Clinical Research

Ayana Rowley Henderson Headshot
Ayana Rowley Henderson
February 11th, 20205 minute read

Read this spotlight on MaryAnn Morgan Cox to learn more about how women in STEM are making a difference.

WhatisClinicalTrials.gov FeatureImage 9Jan2020-01

Infographic: What is ClinicalTrials.gov?

Ayana Rowley Henderson Headshot
Ayana Rowley Henderson
February 4th, 20204 minute read

2020 marks the 20th anniversary of the site, but what were the site's origins and intentions?

BackToSchool Protocol FeatureImage 27Aug2019-01

What is a Protocol in Clinical Trials?

Susan Gilchrist headshot square
Susan Gilchrist
December 10th, 20195 minute read

Have you ever wondered how schedules, tests, and the information ever comes together in clinical trial? It all starts with a clinical trial protocol.

SCRSInterviewBlog FeatureImage 27Nov2019

Clinical Trials 2020 trends, as told by #SCRS19

BlogAuthor Don2 3Dec2019
Don Harder
December 5th, 20197 minute read

After attending SCRS19, four key insights emerged for clinical trials in 2020 and beyond.